Construction and evaluation of rats’ tolerogenic dendritic cells (DC) induced by NF-κB Decoy method

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Construction and evaluation of rats' tolerogenic dendritic cells (DC) induced by NF-κB Decoy method.

AIMS To construct and evaluate rats' tolerogenic dendritic cells (DC) through induction by NF-κB Decoy method. METHODS GM-CSF and IL-4 were used to transform rats's monocytes into DC, and DC were stimulated with LPS, NF-κB Decoy ODN, and loaded with Bovine Type II Collagen. The following methods were employed to phenotype DC: 1) Observation of cell morphology; 2) Evaluation of cell viability ...

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Amelioration of collagen-induced arthritis using antigen-loaded dendritic cells modified with NF-κB decoy oligodeoxynucleotides

Dendritic cells (DCs) play an important role in the initiation of autoimmunity in rheumatoid arthritis (RA); therefore, the use of DCs needs to be explored to develop new therapeutic approaches for RA. Here, we investigated the therapeutic effect of bovine type II collagen (BIIC)-loaded DCs modified with NF-κB decoy oligodeoxynucleotides (ODNs) on collagen-induced arthritis (CIA) in rats and ex...

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Ozone therapy could attenuate tubulointerstitial injury in adenine-induced CKD rats by mediating Nrf2 and NF-κB

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Apoptosis of dendritic cells induced by decoy receptor 3 (DcR3).

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CD40 Knocked Down Tolerogenic Dendritic Cells Decrease Diabetic Injury

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ژورنال

عنوان ژورنال: African Health Sciences

سال: 2014

ISSN: 1680-6905

DOI: 10.4314/ahs.v14i3.18